USAmerican
- Yeni Alvarez: Viperine Gorgon
- Laura Bailey: Lagoona Blue, Headless Headmistress Bloodgood, Skelita Calaveras, Honey Swamp
- Troy Baker: Lou Zarr
- Ogie Banks: Clawd Wolf
- Cam Clarke: Heath Burns, Rotter, HooDude VooDoo, Goon #2, Bram Devein, Clouds
- Debi Derryberry: Draculaura
- Andrew Duncan : Gary
- Erin Fitzgerald: Spectra Vondergeist, Abbey Bominable, C.A. Cupid, Rochelle Goyle, Scarah Screams, Wydowna Spider
- Jonquil Goode: Gigi Grant, Whisp, Twyla, Clawdia Wolf
- Dee Dee Green: Draculaura (TV specials - Ghouls Rule and Scaris: City of Frights)
- Marcus Griffin: Clawd Wolf (TV specials - 13 Wishes - Frights, camera, action!)
- Missi Hale: Catty Noir
- Celeste Henderson: Clawdeen Wolf, Cleo de Nile (TV specials - Scaris: City of Frights and onwards)
- Kate Higgins: Frankie Stein, Catrine DeMew (TV specials - Scaris: City of Frights)
- Julie Maddalena Kliewer: Venus McFlytrap, Robecca Steam
- Wendee Lee: Nefera de Nile, Crabgrass
- Jonathan Lipow: Valentine, Tiki
- Yuri Lowenthal: Deuce Gorgon, Gillington "Gil" Webber, Heath Burns, Clawd Wolf, Bram Devein, Rotter
- George Newbern: Andy Beast
- Audu Paden: Ghoulia Yelps, Sloman "Slo Mo" Mortavitch, Manny Taur, Don of the Dead, Nightmare
- Cindy Robinson: Jackson Jekyll, Holt Hyde, Gory Fangtell, Operetta
- Salli Saffioti: Cleo de Nile, Clawdeen Wolf
- Gigi Sarroino: Operetta
- Keith Silverstein: Bartleby Farnum
- Ira Singerman : Eyera, Goon #1
- Stephanie Sheh : Jinafire Long
- Evan Smith: Deuce Gorgon, Gillington "Gil" Webber, Invisi Billy, Rocco, Garrott du Roque
- Haviland Stillwell : Avea Trotter, Vandala Doubloons
- Karen Strassman: Elissabat, Catrine DeMew
- Sue Swan: Draculaura (TV specials - 13 Wishes - Frights, camera, action!)
- America Young : Toralei Stripe, Howleen Wolf, Meowlody, Purrsephone